The themes chosen by Giotto and the layout of the scenes create a narrative cycle alluding to salvation, full of corresponding and parallel elements, symbolic meanings and formal innovations, all of which can be interpreted in a number of ways and with different nuances of meaning.

The whole cycle was completed in about two years - an astonishingly short time which can only be explained by Giotto's complete technical mastery and a radically new type of site organisation. It seems likely that Giotto drew heavily on his previous experience in Assisi to carry out the Scrovegni cycle.

A new way of painting but also employing ancient Roman techniques and the use of clever devices to give the whole cycle a smooth-flowing unity. In this way, Giotto radically changed the traditional Byzantine approach, moving on to a new concept of painting.

The Golden legend, the Apocrypha as well as classical works and texts from the Franciscan devotional rite. The iconography of the decoration is clearly the work of a man who was well-versed in theological matters.